Cyclopropyl 2-fluorobenzyl ketone

Cyclopropyl 2-fluorobenzyl ketone e sebelisoa e le karolo e bohareng ea Prasugrel.
Prasugrel ke thiophenopyridine antiplatelet e entsoeng ke Eli Lilly le daiichisankyo, moetsi oa meriana oa Japane.Ke sethethefatsi se tlang pele.E theha molek'hule e sebetsang ka mor'a metabolism ka cytochrome P450 sebeteng 'me e kopana le platelet P2Y12 receptor ho sebetsa ka matla khahlanong le platelet aggregation.Boithuto ba bongaka bo bonts'itse hore tekanyetso ea 60 mg e na le phello e ntle ea anticoagulant ho feta 300 mg le 600 mg e ekelitsoeng ea clopidogrel, e ka fokotsang kotsi e felletseng ea lefu la pelo, stroke le lefu ka 20% ka lebaka la lefu la pelo, mme e na le phello e potlakileng. , phello e ntle ea ho phekola, ho hanyetsa lithethefatsi hantle le bioavailability, le chefo e tlaase.