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5 - [2-cyclopropyl-1-(2-fluorophenyl) -2-oxoethyl] - 5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2 (4h) -e le 'ngoe

5 - [2-cyclopropyl-1-(2-fluorophenyl) -2-oxoethyl] - 5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2 (4h) -e le 'ngoe

Tlhaloso e Khutšoanyane:

CAS no: 150322-38-6

Lintho tsa lik'hemik'hale: Prasugrel Intermediates


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Lisebelisoa

5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl] - 5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2 (4h) -e sebelisoa e le bohareng ba Prasugrel
Prasugrel ke thiophenopyridine antiplatelet e entsoeng ke Eli Lilly le daiichisankyo, moetsi oa meriana oa Japane.Ke sethethefatsi se tlang pele.E theha molek'hule e sebetsang ka mor'a metabolism ka cytochrome P450 sebeteng 'me e kopana le platelet P2Y12 receptor ho sebetsa ka matla khahlanong le platelet aggregation.Boithuto ba bongaka bo bonts'itse hore tekanyetso ea 60 mg e na le phello e ntle ea anticoagulant ho feta 300 mg le 600 mg e ekelitsoeng ea clopidogrel, e ka fokotsang kotsi e felletseng ea lefu la pelo, stroke le lefu ka 20% ka lebaka la lefu la pelo, mme e na le phello e potlakileng. , phello e ntle ea ho phekola, ho hanyetsa lithethefatsi hantle le bioavailability, le chefo e tlaase.


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