pentamethylene bis[1-(3,4-dimethoxybenzyl) -3,4-dihydro-6,7-dimethoxy-1H-isoquinoline-2-propionate], dioxalate

pentamethylene bis [1- (3,4-dimethoxybenzyl) -3,4-dihydro-6,7-dimethoxy-1H-isoquinoline-2-propionate], dioxalate e sebelisoa e le bohareng ba Cisatracurium besylate.
Cisatracurium besylate ke mofuta oa letsoai oa benzene sulfonate oa atracurium.Ke mofuta oa li-relaxation tsa mesifa tse entsoeng ka maiketsetso tse sa thekeseleng ka karolo ea eona e ts'oanang le ea tubocurarine.E na le nako ea ho qala ea motsotso o le 1 le nako ea nako ea metsotso e 15.Tekanyetso ea kalafo ha e ame pelo, sebete le tšebetso ea liphio.Hape ha e na thepa ea ho bokella.E ka boela ea etsa hore histamine e lokolloe ha e sebelisoa ka tekanyo e kholo.Bakeng sa ho phomola ha mesifa kapa ho laola ho phefumoloha ho hlokahalang ha ho buuoa, ha ho bapisoa le meriana e mengata ea hona joale ea meriana e fokotsang mesifa, cisatracurium besylate ha e na metabolized ka sebete kapa liphio, 'me e na le botsitso ba pelo;phello ea eona ea ho phomola ha mesifa e matla ka makhetlo a 3 joaloka atracurium ntle le litla-morao tsa pelo.Cisatracurium besylate e sebelisoa haholo-holo ho anesthesia e tloaelehileng, 'me e ka sebelisoa haholo ho intubation, ho phekola ho se sebetse ha sebete le liphio, ho sebelisoa ho buuoa ka pelo le bakuli ba tsofetseng le ba bana.
Ha ho bapisoa le atracurium, sehlahisoa sena ha se na liphello tse mpe tse itšetlehileng ka tekanyo ea ho lokolloa ha histamine;Leha ho le joalo, bothata ke hore bakuli ba nang le bothata ba sebete le liphio ba lokela ho fana ka tlhokomelo ka hloko.
Ho tloha ka 1996 ka lekhetlo la pele ha sethethefatsi sena se kena 'marakeng UK, linaha tsa linaha tse ling li se li sebelisitse butle-butle ho nka sebaka sa vecuronium le atracurium e le tsona tse ka sehloohong tsa ho phomola mesifa ea kliniki.