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Ethylmethyl-carbamic chloride

Ethylmethyl-carbamic chloride

Tlhaloso e Khutšoanyane:

CAS no: 42252-34-6

Lintho tsa lik'hemik'hale: Rivastigmine tartrate Intermediates


Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Lisebelisoa

Ethylmethyl-carbamic chloride e sebelisoa e le karolo e bohareng ea Rivastigmine tartrate.
Rivastigmine tartrate ke rivastigmine lefu la Alzheimer lithethefatsi, rivastigmine ke physostigmine derivative ke Novartis ka lekhetlo la pele ka katleho ntshetswa pele lebitso la khoebo Exelon (exelon), molek'hule le moo carbamate sebopeho, ke mofuta oa amino acid ea selective cerebral cholinesterase inhibitor, e ka boela ea thibela. the acetylcholinesterase le butyrylcholinesterase, cholinergic neurons ka ho liehisa ho lokolloa ha acetylcholine degradation le matla a khothalletsang cholinergic nerve conduction, e ka ntlafatsa mathata a ts'ebetso ea kelello a kenngoeng ke cholinergic, kahoo e ntlafatsa ts'ebetso ea kelello ea bakuli ba lefu la Alzheimer's.Rivastigmine plasma e tlamang protheine e fokola, habonolo ka mokoallo oa mali-boko, o nang le tekanyo e phahameng ea khetho ea boko.Ha e khetholle feela hore e sebetsa ho cerebral cortex le hippocampus e amehang habonolo, empa hape e thibela ka mokhoa o ikhethileng mofuta o ka sehloohong oa AChE bokong, e leng se bakang phokotso ea katleho ea litla-morao tsa peripheral cholinergic.Rivastigmine in vivo halofo ea bophelo ke nako e khuts'oane le e telele ea ketso.Ho fapana le tacrine, sehlahisoa sena se hippocampus le cortex ea G1 enzyme inhibitory effect se matla.Tleliniki bakeng sa kalafo ea 'dementia' e bobebe ho isa ho e itekanetseng ea mofuta oa Alzheimer, kapa lefu la Alzheimer's ho ka belaelloa hore ke lefu la Alzheimer's Clinical.

Mohloli o kopantsoeng oa Sehlahisoa

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Setifikeiti

JIN DUN Medical o na leHo tšoaneleha ha ISO mme e kopana le litekanyetso tsa tlhahiso ea GMP, e hirileng litsebi tsa ka hare ho naha le tsa kantle ho naha tse nang le boiphihlelo bo bongata ho tataisa R&D ea k'hamphani.

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Melemo mabapi le ho Itloaetsa Meriana

THEKNOL OGY MELEMO
● High Pressure Catalytic Hydrogenation .Khatello e Phahameng ea Hydrogenolysis Reaction .Mehato ea Cryogenic (<-78%C)
● Monko o monate oa Heterocyclic Synthesis
● Karabelo ea ho Rulahanya bocha
●Chiral Resolution
●Heck, Suzuki,Negishi,Sonogashira .Giignard Reaction

JIN DUN R&D

Thepa

Lab ea rona e na le lisebelisoa tse fapaneng tsa liteko le liteko, joalo ka: NMR (Bruker 400M), HPLC, chiral-HPLC, LC-MS, LC-MS/MS (API 4000), IR, UV, GC, GC-MS, Chromatography, Microwave Synthesizer, Parallel Synthesizer, Differential Scanning Calorimeter (DSC), Electron microscope...

Sehlopha sa R&D

Jindun Medical e na le sehlopha sa basebetsi ba profeshenale ba R&D, 'me e sebelisa litsebi tse ngata tsa lapeng le kantle ho naha ho tataisa R&D, ho etsa hore pokello ea rona e nepahale le ho sebetsa hantle.

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Karolelano ea Nyeoe

Re thusitse lik'hamphani tse ngata tse phahameng tsa malapeng tsa meriana, tse kangHansoh, Hengrui le HEC Pharm.Mona re tla bontša karolo ea bona.

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Customization Case One:

Cas No.: 110351-94-5

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Taba ea Bobeli ea Tloaelo:

Cas No.: 144848-24-8

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Taba ea Boraro ea Tloaelo:

Cas No.: 200636-54-0

Mokhoa oa Tšebelisano

1.Iketsetse Li-Intermediate tse Ncha kapa li-API.Joalo ka ho arolelana linyeoe tse kaholimo, bareki ba na le litlhoko tsa li-Intermediates kapa li-API, 'me ha ba khone ho fumana lihlahisoa tse hlokahalang' marakeng, joale re ka thusa ho Customize.

2.Ntlafatso ea Ts'ebetso ea Lihlahisoa tsa Khale.Sehlopha sa rona se tla thusa ho ntlafatsa le ho ntlafatsa tlhahiso e joalo eo tsela ea eona ea ho arabela e leng ea khale, litšenyehelo tsa tlhahiso li phahame, 'me katleho e tlaase.Re ka fana ka litokomane tse felletseng bakeng sa phetisetso ea theknoloji le ntlafatso ea ts'ebetso, re thusa moreki bakeng sa tlhahiso e sebetsang hantle.

Ho tloha ho sepheo sa lithethefatsi ho isa ho INDs, JIN DUN Medical e u falitharollo tsa motho ka mong tsa R&D.

JIN DUN Medical e tsitlallela ho theha sehlopha se nang le litoro, ho etsa lihlahisoa tse nang le seriti, tse hlokolosi, tse thata, le ho tsoa bohle ho ba molekane ea tšepahalang le motsoalle oa bareki!


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