2-butyl-5-nitro-3-benzofuranyl) [4-[3-(dibutylaMino) propoxy]phenyl]

E sebelisoa ka kliniki ho hyperuricemia ea mantlha le ea bobeli, haholo-holo ho bakuli ba nang le hyperuricemia, hammoho le ho bakuli ba nang le ho se sebetse hantle ha renal, le ho bakuli ba nang le gout e iphetang kapa e sa foleng, hammoho le ho bakuli ba nang le Hyperuricemia.E sebelisoa ho bakuli ba nang le Gouty nephropathy ho imolla matšoao le ho fokotsa sebopeho sa majoe a renal uric acid;majoe a gout;e sebelisoang ho uric acid ea liphio le lefu la liphio la uric acid.

Sethethefatsi se secha sa anti-arrhythmic Atrial fibrillation (AF) ke lefu le ka 'nang la beha bophelo kotsing.Ka lebaka la botsofali ba baahi, liketsahalo tsa lefats'e le lefu la atrial fibrillation li ntse li eketseha, 'me e fetohile mathata a macha a Bophelo bo botle ba sechaba.Ho na le bakuli ba limilione tse 2.5 ba nang le atrial fibrillation United States le limilione tse 4.5 European Union.Ho ea ka lipalo-palo, ho ata ha atrial fibrillation har'a batho ba fetang lilemo tse 30 naheng ea heso ke 0,77%, e ntseng e eketseha ka lilemo, 'me banna ba phahametse basali (0.9%: 0.7%).Mafu a bakang ho ferekana ha atria haholo-holo a akarelletsa khatello ea mali, lefu la pelo, lefu la pelo la valvular, lefu la pelo le sa foleng le sa tloaelehang, le ho hloleha ha pelo.Letšoao le ka sehloohong la bakuli ba nang le atrial fibrillation ke lebelo le sa tloaelehang la ventricular, 'me ho laola lebelo la pelo ho nka boemo bo itseng kalafong e matla le tlhokomelo ea matšoao.Amiodarone e phetha karolo e ntle ea ho laola lebelo la pelo le ho tsosolosa morethetho oa sinus, empa liphello tse mpe tsa litho tse lebisitsoeng tse amanang le karolo ea iodine mohahong oa eona li fokotsa tšebeliso ea eona ea bongaka, e kang tšenyo ea matšoafo, qoqotho le sebete.Liphetoho tse mpe tse boletsoeng ka holimo le sebopeho sa eona The iodine in e amana haufi-ufi.Sethethefatsi se secha sa antiarrhythmic Dronedarone (Dronedarone) se fumanoe ka ho fetola sebopeho sa amiodarone.Dronedarone e na le lisebelisoa tsa electrophysiological tse ts'oanang le amiodarone, empa ha e na iodine ka sebopeho sa eona, kahoo e ka qoba litla-morao tse tebileng tsa extra-cardiac tse bakoang ke iodine Chemicalbook.Dronedarone e ile ea amoheloa bakeng sa ho rekisoa ke US Food and Drug Administration (FDA) ka July 2009, 'me ea amoheloa bakeng sa ho rekisoa European Union ho 2009. Hape ke lithethefatsi tsa pele tse ncha tsa antiarrhythmic tse amoheloang European Union ka lilemo tse 10.Dronedarone ke N-[2-butyl-3-[4-[3-(dibutylamino) propoxy]phenyl] -5-benzofuranyl]-methanesulfonamide, e leng ho fokotsa motsoako oa benzofuran o fumanoang ka ho fetola sebopeho sa amiodarone, e seng karabelo e mpe ea pelo.E tlosa athomo ea iodine ho amiodarone ho fokotsa chefo ea qoqotho le litho tse ling;e eketsa sehlopha sa methylsulfonyl ka lehlakoreng la benzofuran ho fokotsa lipophilicity, kahoo e khutsufatsa halofo ea bophelo ba lithethefatsi le ho fokotsa phello ea ho bokella lisele le monyetla oa lithethefatsi Of neurotoxicity.Ka bobeli 2011 US version le 2010 Europe version ea Atrial Fibrillation Guidelines e khothalletsa dronedarone bakeng sa phekolo ea atrial fibrillation.Dronedarone e bolokehile ebile e sebetsa hantle ho phekola sekhahla sa ventricular le ho boloka sekhahla sa sinus ho bakuli ba fapaneng ntle le AF e matla.E ka ba lithethefatsi tse sebetsang ho nkela amiodarone sebaka.Dronedarone e ka boela ea fokotsa lefu la bakuli ba AF esita le bakuli ba AF ba sa khaotseng.Ka hona, ho lebelletsoe hore e be moriana oa pele ho bakuli ba AF ntle le ho hloleha ho matla ha pelo.Ho feta moo, ts'ebeliso ea li-anticoagulants ho bakuli ba AF ba kotsing e bohareng e na le molemo ho ts'ebeliso ea dronedarone.