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3,5-di-o-benzoyl-2-deoxy-2,2-difluoro-1-o-met hane- sulfonyl-d-ribofuranose

3,5-di-o-benzoyl-2-deoxy-2,2-difluoro-1-o-met hane- sulfonyl-d-ribofuranose

Tlhaloso e Khutšoanyane:

CAS no: 134877-43-3

Lintho tsa lik'hemik'hale: Gemcitabine Intermediates


Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Lisebelisoa

3,5-di-o-benzoyl-2-deoxy-2,2-difluoro-1-o-met hane-sulfonyl-d-ribofuranose e sebelisoa e le bohareng ba Gemcitabine.
Gemcitabine ke analogue ea pyrimidine nucleotide, e leng karolo ea lithethefatsi tse thibelang metabolic.E ka thibela tsoelo-pele ea motsoako oa DNA ka nako e itseng, ke hore, S-phase.E na le litšoaneleho tsa mefuta e mengata ea anticancer, mokhoa o ikhethileng oa ts'ebetso, chefo e tlase, ha e na ho hanyetsana le lithethefatsi tse ling tsa chemotherapeutic ebile ha e na chefo e kholo.Kajeno, gemcitabine e amohetsoe hore e sebelisoe linaheng tse fetang 90, e fetoha moriana oa pele oa kalafo ea mofets'e oa matšoafo oa sele e seng e nyane le "tekanyetso ea khauta" bakeng sa kalafo ea mofets'e oa pancreatic.

Mohloli o kopantsoeng oa Sehlahisoa

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Setifikeiti

JIN DUN Medical o na leHo tšoaneleha ha ISO mme e kopana le litekanyetso tsa tlhahiso ea GMP, e hirileng litsebi tsa ka hare ho naha le tsa kantle ho naha tse nang le boiphihlelo bo bongata ho tataisa R&D ea k'hamphani.

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Melemo mabapi le ho Itloaetsa Meriana

THEKNOL OGY MELEMO
● High Pressure Catalytic Hydrogenation .Khatello e Phahameng ea Hydrogenolysis Reaction .Mehato ea Cryogenic (<-78%C)
● Monko o monate oa Heterocyclic Synthesis
● Karabelo ea ho Rulahanya bocha
●Chiral Resolution
●Heck, Suzuki,Negishi,Sonogashira .Giignard Reaction

JIN DUN R&D

Thepa

Lab ea rona e na le lisebelisoa tse fapaneng tsa liteko le liteko, joalo ka: NMR (Bruker 400M), HPLC, chiral-HPLC, LC-MS, LC-MS/MS (API 4000), IR, UV, GC, GC-MS, Chromatography, Microwave Synthesizer, Parallel Synthesizer, Differential Scanning Calorimeter (DSC), Electron microscope...

Sehlopha sa R&D

Jindun Medical e na le sehlopha sa basebetsi ba profeshenale ba R&D, 'me e sebelisa litsebi tse ngata tsa lapeng le kantle ho naha ho tataisa R&D, ho etsa hore pokello ea rona e nepahale le ho sebetsa hantle.

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Karolelano ea Nyeoe

Re thusitse lik'hamphani tse ngata tse phahameng tsa malapeng tsa meriana, tse kangHansoh, Hengrui le HEC Pharm.Mona re tla bontša karolo ea bona.

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Customization Case One:

Cas No.: 110351-94-5

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Taba ea Bobeli ea Tloaelo:

Cas No.: 144848-24-8

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Taba ea Boraro ea Tloaelo:

Cas No.: 200636-54-0

Mokhoa oa Tšebelisano

1.Iketsetse Li-Intermediate tse Ncha kapa li-API.Joalo ka ho arolelana linyeoe tse kaholimo, bareki ba na le litlhoko tsa li-Intermediates kapa li-API, 'me ha ba khone ho fumana lihlahisoa tse hlokahalang' marakeng, joale re ka thusa ho Customize.

2.Ntlafatso ea Ts'ebetso ea Lihlahisoa tsa Khale.Sehlopha sa rona se tla thusa ho ntlafatsa le ho ntlafatsa tlhahiso e joalo eo tsela ea eona ea ho arabela e leng ea khale, litšenyehelo tsa tlhahiso li phahame, 'me katleho e tlaase.Re ka fana ka litokomane tse felletseng bakeng sa phetisetso ea theknoloji le ntlafatso ea ts'ebetso, re thusa moreki bakeng sa tlhahiso e sebetsang hantle.

Ho tloha ho sepheo sa lithethefatsi ho isa ho INDs, JIN DUN Medical e u falitharollo tsa motho ka mong tsa R&D.

JIN DUN Medical e tsitlallela ho theha sehlopha se nang le litoro, ho etsa lihlahisoa tse nang le seriti, tse hlokolosi, tse thata, le ho tsoa bohle ho ba molekane ea tšepahalang le motsoalle oa bareki!


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