3-(1-(Dimethylamino)ethyl]phenol

3-(1-(Dimethylamino)ethyl]phenol e sebelisoa e le bohareng ba Rivastigmine tartrate.
Rivastigmine tartrate ke rivastigmine lefu la Alzheimer lithethefatsi, rivastigmine ke physostigmine derivative ke Novartis ka lekhetlo la pele ka katleho ntshetswa pele lebitso la khoebo Exelon (exelon), molek'hule le moo carbamate sebopeho, ke mofuta oa amino acid ea selective cerebral cholinesterase inhibitor, e ka boela ea thibela. the acetylcholinesterase le butyrylcholinesterase, cholinergic neurons ka ho liehisa ho lokolloa ha acetylcholine degradation le matla a khothalletsang cholinergic nerve conduction, e ka ntlafatsa mathata a ts'ebetso ea kelello a kenngoeng ke cholinergic, kahoo e ntlafatsa ts'ebetso ea kelello ea bakuli ba lefu la Alzheimer's.Rivastigmine plasma e tlamang protheine e fokola, habonolo ka mokoallo oa mali-boko, o nang le tekanyo e phahameng ea khetho ea boko.Ha e khetholle feela hore e sebetsa ho cerebral cortex le hippocampus e amehang habonolo, empa hape e thibela ka mokhoa o ikhethileng mofuta o ka sehloohong oa AChE bokong, e leng se bakang phokotso ea katleho ea litla-morao tsa peripheral cholinergic.Rivastigmine in vivo halofo ea bophelo ke nako e khuts'oane le e telele ea ketso.Ho fapana le tacrine, sehlahisoa sena se hippocampus le cortex ea G1 enzyme inhibitory effect se matla.Tleliniki bakeng sa kalafo ea 'dementia' e bobebe ho isa ho e itekanetseng ea mofuta oa Alzheimer, kapa lefu la Alzheimer's ho ka belaelloa hore ke lefu la Alzheimer's Clinical.