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2-deoxy-2,2-difluoro-d-ribofuranose-3,5-dib enzoate

2-deoxy-2,2-difluoro-d-ribofuranose-3,5-dib enzoate

Tlhaloso e Khutšoanyane:

CAS no: 153012-08-9

Lintho tsa lik'hemik'hale: Gemcitabine Intermediates


Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Lisebelisoa

2-deoxy-2,2-difluoro-d-ribofuranose-3,5-dib enzoate e sebelisoa e le bohareng ba Gemcitabine.
Gemcitabine ke analogue ea pyrimidine nucleotide, e leng karolo ea lithethefatsi tse thibelang metabolic.E ka thibela tsoelo-pele ea motsoako oa DNA ka nako e itseng, ke hore, S-phase.E na le litšoaneleho tsa mefuta e mengata ea anticancer, mokhoa o ikhethileng oa ts'ebetso, chefo e tlase, ha e na ho hanyetsana le lithethefatsi tse ling tsa chemotherapeutic ebile ha e na chefo e kholo.Kajeno, gemcitabine e amohetsoe hore e sebelisoe linaheng tse fetang 90, e fetoha moriana oa pele oa kalafo ea mofets'e oa matšoafo oa sele e seng e nyane le "tekanyetso ea khauta" bakeng sa kalafo ea mofets'e oa pancreatic.


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