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2-bromo-2-(2-fluorophenyl)-1-cyclopropylethanone

2-bromo-2-(2-fluorophenyl)-1-cyclopropylethanone

Tlhaloso e Khutšoanyane:

CAS no:204205-33-4

Lintho tsa lik'hemik'hale: Prasugrel Intermediates


Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Lisebelisoa

2-bromo-2- (2-fluorophenyl) -1-cyclopropylethanone e sebelisoa e le bohareng ba Prasugrel.
Prasugrel ke thiophenopyridine antiplatelet e entsoeng ke Eli Lilly le daiichisankyo, moetsi oa meriana oa Japane.Ke sethethefatsi se tlang pele.E theha molek'hule e sebetsang ka mor'a metabolism ka cytochrome P450 sebeteng 'me e kopana le platelet P2Y12 receptor ho sebetsa ka matla khahlanong le platelet aggregation.Boithuto ba bongaka bo bonts'itse hore tekanyetso ea 60 mg e na le phello e ntle ea anticoagulant ho feta 300 mg le 600 mg e ekelitsoeng ea clopidogrel, e ka fokotsang kotsi e felletseng ea lefu la pelo, stroke le lefu ka 20% ka lebaka la lefu la pelo, mme e na le phello e potlakileng. , phello e ntle ea ho phekola, ho hanyetsa lithethefatsi hantle le bioavailability, le chefo e tlaase.


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