Rivaroxaban(S)-Rivaroxaban;BAY 59-7939;RivaroxabanIsomer;Rivaroxaban;
Rivaroxaban(S)-Rivaroxaban;BAY 59-7939;RivaroxabanIsomer;Rivaroxaban;
E sebelisoa ho bakuli ba baholo ba nang le opereishene e khethehileng ea letheka kapa lengole ho thibela venous thrombosis (VTE).
E sebelisetsoa ho thibela kapa ho fokotsa ho thehoa ha thrombosis, deep vein thrombosis (DVT) le pulmonary embolism (PE) ka mor'a ho buuoa ka letheka kapa lengole.
Tekanyo e khothalletsoang ke molomo oa rivaroxaban 10mg, hang ka letsatsi.Rivaroxaban 10mg e ka nkoa ka lijo kapa e le mong.Lipilisi tsa Rivaroxaban 15mg kapa 20mg li lokela ho nkoa ka lijo.
standard: usp40
Tekanyo: 99-102%
Kantle: Phofo e tšoeu
Pakete: 25kg / moropa
Nka 4-(4-aminophenyl) morpholin-3-one (SM-1), (S)-N-glycidyl phthalimide (SM-2), 5-chlorothiophene-2- Formyl chloride (SM-3) ke lintho tse qalang. .Ka mor'a condensation, cyclization, aminolysis le acylation, rivaroxaban e tala e fumanoa, 'me rivaroxaban e felile e hloekisoa.
Boitokisetso: Sehlahisoa sena ke letlapa le khubelu le koahetsoeng ka filimi.
Lisebelisoa:
Letlapa la mantlha: selulose ea microcrystalline, croscarmellose sodium, lactose monohydrate, hypromellose, sodium lauryl sulfate, magnesium stearate.
Ho roala: polyethylene glycol, hypromellose, titanium dioxide, tšepe oxide e khubelu.
Rivaroxaban ke lithethefatsi tse khethang haholo, tse nooang ka ho toba tse thibelang factor Xa.Ka khetho e phahameng le e nang le tlholisano ea tlholisano ea ntho ea mahala le e tlamiloeng ea Xa le ts'ebetso ea prothrombin, lelefatsa nako ea nako ea thromboplastin (PT) le nako ea prothrombin (aPTT) ka mokhoa o itšetlehileng ka lethal dose, e ka sitisang phororo ea coagulation. thibela tlhahiso ea thrombin le thrombosis.Rivaroxaban ha e thibele thrombin (activating factor Ⅱ), leha e le hore e na le phello e matla ho liplatelete.
Phapang ea bohlokoa pakeng tsa rivaroxaban le fondaparinux/heparin ke hore ha e hloke ho kenya letsoho ha antithrombin III 'me e ka hanyetsa ka ho toba ntho e sa lefelloeng le e tlamiloeng Xa;ha heparin e hloka hore antithrombin III e sebetse, 'me ha e na phello ho factor Xa prothrombin complex.
JIN DUN Medical o na leHo tšoaneleha ha ISO mme e kopana le litekanyetso tsa tlhahiso ea GMP, e hirileng litsebi tsa ka hare ho naha le tsa kantle ho naha tse nang le boiphihlelo bo bongata ho tataisa R&D ea k'hamphani.
THEKNOL OGY MELEMO
● High Pressure Catalytic Hydrogenation .Khatello e Phahameng ea Hydrogenolysis Reaction .Mehato ea Cryogenic (<-78%C)
● Monko o monate oa Heterocyclic Synthesis
● Karabelo ea ho Rulahanya bocha
●Chiral Resolution
●Heck, Suzuki,Negishi,Sonogashira .Giignard Reaction
Thepa
Lab ea rona e na le lisebelisoa tse fapaneng tsa liteko le liteko, joalo ka: NMR (Bruker 400M), HPLC, chiral-HPLC, LC-MS, LC-MS/MS (API 4000), IR, UV, GC, GC-MS, Chromatography, Microwave Synthesizer, Parallel Synthesizer, Differential Scanning Calorimeter (DSC), Electron microscope...
Sehlopha sa R&D
Jindun Medical e na le sehlopha sa basebetsi ba profeshenale ba R&D, 'me e sebelisa litsebi tse ngata tsa lapeng le kantle ho naha ho tataisa R&D, ho etsa hore pokello ea rona e nepahale le ho sebetsa hantle.
Re thusitse lik'hamphani tse ngata tse phahameng tsa malapeng tsa meriana, tse kangHansoh, Hengrui le HEC Pharm.Mona re tla bontša karolo ea bona.
Customization Case One:
Cas No.: 110351-94-5
Taba ea Bobeli ea Tloaelo:
Cas No.: 144848-24-8
Taba ea Boraro ea Tloaelo:
Cas No.: 200636-54-0
1.Iketsetse Li-Intermediate tse Ncha kapa li-API.Joalo ka ho arolelana linyeoe tse kaholimo, bareki ba na le litlhoko tsa li-Intermediates kapa li-API, 'me ha ba khone ho fumana lihlahisoa tse hlokahalang' marakeng, joale re ka thusa ho Customize.
2.Ntlafatso ea Ts'ebetso ea Lihlahisoa tsa Khale.Sehlopha sa rona se tla thusa ho ntlafatsa le ho ntlafatsa tlhahiso e joalo eo tsela ea eona ea ho arabela e leng ea khale, litšenyehelo tsa tlhahiso li phahame, 'me katleho e tlaase.Re ka fana ka litokomane tse felletseng bakeng sa phetisetso ea theknoloji le ntlafatso ea ts'ebetso, re thusa moreki bakeng sa tlhahiso e sebetsang hantle.
Ho tloha ho sepheo sa lithethefatsi ho isa ho INDs, JIN DUN Medical e u falitharollo tsa motho ka mong tsa R&D.
JIN DUN Medical e tsitlallela ho theha sehlopha se nang le litoro, ho etsa lihlahisoa tse nang le seriti, tse hlokolosi, tse thata, le ho tsoa bohle ho ba molekane ea tšepahalang le motsoalle oa bareki!
![Casp ungin Acetate;Caspofungin acetate;Cancidas;Caspofungin acetate [USAN:BAN:JAN];](http://cdn.globalso.com/jindunchem-med/fbe17385-300x300.jpg)