Haufinyane ho Fihla 4-Biphenylcarboxylic Acid (92-92-2)

Ka tsamaiso ea rona e hlahelletseng, bokhoni bo matla ba tekheniki le ts'ebetso e tiileng ea ho sebetsana le maemo a holimo, re tsoela pele ho fa bareki ba rona boleng bo botle bo tšepahalang, litheko tse ntle tsa thekiso le lits'ebeletso tse ntle haholo.Re ikemiselitse ho ba e mong oa balekane ba hau ba ikarabellang haholo le ho fumana khotsofalo ea hau bakeng sa Newly Arrival 4-Biphenylcarboxylic Acid (92-92-2), Molao-motheo oa mokhatlo oa rona ke ho fana ka thepa ea boleng bo holimo kamehla, litšebeletso tsa litsebi, le puisano e tšepahalang. .Amohela metsoalle eohle ho etsa liteko tsa ho etsa tšebelisano ea nako e telele ea khoebo.
Ka tsamaiso ea rona e hlahelletseng, bokhoni bo matla ba tekheniki le ts'ebetso e tiileng ea ho sebetsana le maemo a holimo, re tsoela pele ho fa bareki ba rona boleng bo botle bo tšepahalang, litheko tse ntle tsa thekiso le lits'ebeletso tse ntle haholo.Re ikemiselitse ho ba e mong oa balekane ba hau ba ikarabellang le ho fumana khotsofalo ea hau bakeng saChina Organic Synthesis Intermediates, Thepa ea rona e romelloa haholo Asia Boroa-bochabela, Bochabela bo Hare, Amerika Leboea le Europe.Ka sebele boleng ba rona bo tiisitsoe.Haeba u thahasella thepa leha e le efe ea rona kapa u ka rata ho buisana ka taelo e tloaelehileng, etsa bonnete ba hore u ikutloa u lokolohile ho ikopanya le rona.Re labalabela ho theha likamano tse atlehileng tsa khoebo le bareki ba bacha lefatšeng ka bophara haufinyane.

2'-hydroxy-3'-nitro-3-biphenylcarboxylic acid e sebelisoa e le bohareng ba Eltrombopag.
Eltrombopag, e ntlafalitsoeng ke GlaxoSmithKline (GSK) naheng ea UK, 'me hamorao e ile ea ntlafatsoa ka kopanelo le Novartis naheng ea Switzerland, ke molek'hule oa pele o amohetsoeng oa molek'hule o se nang peptide TPO receptor agonist lefatšeng.Eltrombopag e amohetsoe ke US FDA ka 2008 bakeng sa kalafo ea idiopathic thrombocytopenic purpura (ITP), le ka 2014 bakeng sa kalafo ea anemia e matla ea aplastic (AA).Hape ke moriana oa pele o amohetsoeng ke US FDA bakeng sa kalafo ea AA lilemong tse 30 tsa morao tjena.
Ka December 2012, US FDA e ile ea amohela Eltrombopag bakeng sa phekolo ea thrombocytopenia ho bakuli ba nang le lefu la sebete le sa foleng la C (CHC), e le hore bakuli ba hepatitis C ba nang le bokooa bo bobe ka lebaka la palo e tlaase ea platelet ba ka qala le ho boloka phekolo e tloaelehileng ea interferon bakeng sa mafu a sebete.Ka February 3, 2014, GlaxoSmithKline e phatlalalitse hore FDA e fane ka katleho ea meriana ea phekolo ea Eltrombopag bakeng sa phekolo ea hemopenia ho bakuli ba nang le lik'hemik'hale tse matla tsa aplastic anemia (SAA) tse sa kang tsa arabela ka botlalo ho immunotherapy.Ka August 24, 2015, US FDA e amohetse Eltrombopag bakeng sa phekolo ea thrombocytopenia ho batho ba baholo le bana ba lilemo li 1 ho ea holimo ba nang le lefu le sa foleng la immune thrombocytopenia (ITP) ba nang le karabelo e sa lekaneng ho corticosteroids, immunoglobulins kapa splenectomy.Ka January4, 2018, Eltrombopag e ile ea amoheloa hore e ngolisoe Chaena bakeng sa phekolo ea "immune immune thrombocytopenia" (ITP).

Ka tsamaiso ea rona e hlahelletseng, bokhoni bo matla ba tekheniki le ts'ebetso e tiileng ea ho sebetsana le maemo a holimo, re tsoela pele ho fa bareki ba rona boleng bo botle bo tšepahalang, litheko tse ntle tsa thekiso le lits'ebeletso tse ntle haholo.Re ikemiselitse ho ba e mong oa balekane ba hau ba ikarabellang haholo le ho fumana khotsofalo ea hau bakeng sa Newly Arrival 4-Biphenylcarboxylic Acid (92-92-2), Molao-motheo oa mokhatlo oa rona ke ho fana ka thepa ea boleng bo holimo kamehla, litšebeletso tsa litsebi, le puisano e tšepahalang. .Amohela metsoalle eohle ho etsa liteko tsa ho etsa tšebelisano ea nako e telele ea khoebo.
Ho Fihla BochaChina Organic Synthesis Intermediates, Thepa ea rona e romelloa haholo Asia Boroa-bochabela, Bochabela bo Hare, Amerika Leboea le Europe.Ka sebele boleng ba rona bo tiisitsoe.Haeba u thahasella thepa leha e le efe ea rona kapa u ka rata ho buisana ka taelo e tloaelehileng, etsa bonnete ba hore u ikutloa u lokolohile ho ikopanya le rona.Re labalabela ho theha likamano tse atlehileng tsa khoebo le bareki ba bacha lefatšeng ka bophara haufinyane.