MOQ e tlase bakeng sa Thekiso e Chesang!Phepelo ea Feme ea Boleng bo Phahameng Betrixaban Raw Materials CAS 330942-05-7

Tlhaloso e Khutšoanyane:

Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Ho ba sethala sa ho phethahatsa litoro tsa basebetsi ba rona!Ho haha sehlopha se thabileng haholoanyane, se kopaneng le se eketsehileng sa litsebi!Ho fihlela moputso o mong le o mong oa bareki ba rona, barekisi, sechaba le rona bakeng sa Low MOQ bakeng sa Thekiso e Chesang!Feme ea Phepelo ea Boleng bo Phahameng Betrixaban Raw Materials CAS 330942-05-7, Re tšepahala ebile re bulehile.Re lebelletse ho emisa le ho theha kamano ea lerato e tšepahalang le ea nako e telele.
Ho ba sethala sa ho phethahatsa litoro tsa basebetsi ba rona!Ho haha sehlopha se thabileng haholoanyane, se kopaneng le se eketsehileng sa litsebi!Ho fihlela moputso o le mong oa bareki ba rona, barekisi, sechaba le rona bakeng saChina Pharmaceutical Intermediate le 330942-05-7, "Boleng bo botle le theko e utloahalang" ke melao-motheo ea rona ea khoebo.Haeba u thahasella litharollo tsa rona kapa u na le lipotso, hopola ho ikutloa u lokolohile ho ikopanya le rona.Re tšepa ho theha likamano tsa tšebelisano le uena nakong e tlang e haufi.

Fondaparinux Biological Activity

Hlalosa	Fondaparinux sodium ke antithrombin-dependent factor Xa inhibitor.
Tse amanangLihlopha	tsela ea lipontšo >> Li-enzyme/proteases >> Factor Xa Research libaka >> Mafu a pelo
Sepheo	Factor Xa[1]
In vitrolithuto	Fondaparinux sodium ke anticoagulant ea pele e ncha e khethang ho khetha Xa.Bakeng sa Fondaparinux, boleng ba IC50 (anti-Xa IU/ml) ea li-monocyte tse kentsoeng (ac-M) ke 0.59±0.05, le likaroloana tse nkiloeng ho monocyte (MMP) ke 0.17±0.03 [2].
Ka vivolipatlisiso	Fondaparinux sodium e na le profil ea pharmacokinetic e itšetlehileng ka tekanyetso, e fanang ka karabelo e ka tsejoang esale pele.Fondaparinux sodium e na le 100% bioavailability, e na le ts'ebetso e potlakileng, e na le halofo ea bophelo ea lihora tse 14 ho isa ho tse 16, 'me e ka tsoela pele ho hanyetsa thrombosis nakong ea lihora tse 24.Setlhare ha se ame nako ea prothrombin kapa nako e kentsoeng ea karolo ea thromboplastin, ebile ha e ame tšebetso ea liplatelete kapa ho kopanya [1].
Litšupiso	[1].Bauer KA.le al.Fondaparinux sodium: inhibitor e khethang ea factor Xa.Am J Health Syst Pharm.2001 Nov 1;58 Tlatsetso 2:S14-7.[2].Ben-Hadj-Khalifa S, le ba bang.Phapang ea coagulation inhibitory phello ea fondaparinux, enoxaparin le heparin e sa tsitsang mefuteng ea lisele tsa tlhahiso ea thrombin.Mali a Coagul Fibrinolysis.2011 Jul;22(5):369-73.

Lik'hemik'hale le thepa ea 'mele ea Fondaparinux

Mokhoa oa limolek'hule	C31H53N3Na10O49S8
Boima ba molek'hule	1738.16
PSA	900.82000

Fondaparinux ke mofuta o mocha oa moriana oa antithrombotic o amohetsoeng ke FDA kamora heparin le heparin e tlase ea boima ba molek'hule bakeng sa kalafo le thibelo ea mefuta e fapaneng ea arteriovenous thrombosis.

Lipontšo: Fondaparinux e sebelisetsoa bakuli ba etsoang opereishene e kholo ea masapo ea maoto le matsoho a ka tlaase, joalo ka ho robeha ha letheka, ho buuoa ka lengole le leholo kapa ho fetola letheka, ho thibela venous thromboembolism.E sebelisetsoa ho phekola bakuli ba nang le angina e sa tsitsang kapa ba se nang ST-segment elevation myocardial infarction ba kenang ka potlako (<120 metsotso) kalafo e hlaselang (PCI) ntle le pontšo.E sebelisoa bakeng sa kalafo ea bakuli ba nang le ST-segment elevation myocardial infarction ba sebelisang thrombolysis kapa qalong ba sa fumaneng mefuta e meng ea kalafo ea reperfusion.

1) Kholiso e tsoelang pele ea 'maraka ea Glaxo e tla e beha boemong ba mantlha ba lithethefatsi tseleng e latelang ea bongaka ea Lekala la Bophelo, phetoho ea theko ea Khomishene ea Naha ea Nts'etsopele le Phetoho, le inshorense ea bongaka ea Lekala la People's Insurance.

A、Sehlahisoa ha se so kene ho inshorense ea bongaka ea naha.Ka 2010, tokiso ea inshorense ea bongaka e sa tsoa kenya inshorense ea lehae ea liprofinse tse 16.Lithekiso li boemong ba pele 'me butle-butle li tla nka sebaka sa' maraka oa heparin oa boima bo tlase ba limolek'hule;liprofinse tsa inshorense ea bongaka: Shaanxi, Shanxi, Inner Mongolia, Liaoning, Tibet, Yunnan, Guangdong , Guangxi, Hainan, Jiangsu, Gansu, Fujian, Jiangxi, Henan, Hubei, Beijing.

B, Lipontšo li ntse li eketseha.GSK hajoale e na le matšoao a 3 tleliniking.Ka mohlala, matšoao a li-stents a lumelloa feela.Li-heparin tse ling ha li fumanehe.Ts'ebeliso ea bongaka ea li-stents e eketseha ka 30% selemo se seng le se seng.Ka tumello ea lipontšo tse ncha, thekiso e tla eketseha.Ka khopolo, mafu 'ohle a tšoaroang ke lihlahisoa tsa lihlopha tsa heparin a ka phekoloa ke sehlahisoa sena.

C, Theko e molemo, theko e tlaase ea sehlahisoa sena 'marakeng oa US ke lidolara tse 132 tsa US, Chaena ke li-yuan tse 168, theko ea malapeng e ke ke ea theoha.Haeba u reka kantle ho naha, 'maraka oa machabeng o na le sebaka se pharaletseng;

2) Tekanyo ea tekheniki e phahame, thepa e tala e entsoe ka mehato e 75, 'me patent e felile ka lilemo tse 5 (sengoloa sa 2014).Ha e so amoheloe ke bahlahisi ba bang.The synthesis e thata haholo.E ke ke ea etsoa ka tlase ho lilemo tse 10.Potoloho e telele, e thata, ebile e tsetela.hodimo.Ho na le bahlolisani ba seng bakae ba lehae, mme bahlolisani ba kantle ho naha ba na le litšenyehelo tse phahameng tsa thepa e tala.Sepheo sa rona ke ho tsoela pele ho fokotsa litšenyehelo tsa thepa e tala le ho nkela Glaxo sebakeng sa tlhahiso ea thepa e tala.
Hengrui Pharmaceuticals Fondaparinux e amohetsoe e le mohlala oa pele oa ho etsisa China 2018.
Guangdong Runxing Biotechnology Co., Ltd. e na le tlhahiso ea selemo le selemo ea 210 kg ea fondaparinux sodium e tsoetseng pele ea mahareng N3, e tla kenngoa ka 2018.

Fondaparinux qalong e qapiloe ke MYLAN IRELAND.Hajoale, Hengrui Pharmaceuticals, Borui Pharmaceuticals, Haisco.

Ho ba sethala sa ho phethahatsa litoro tsa basebetsi ba rona!Ho haha sehlopha se thabileng haholoanyane, se kopaneng le se eketsehileng sa litsebi!Ho fihlela moputso o mong le o mong oa bareki ba rona, barekisi, sechaba le rona bakeng sa Low MOQ bakeng sa Thekiso e Chesang!Feme ea Phepelo ea Boleng bo Phahameng Betrixaban Raw Materials CAS 330942-05-7, Re tšepahala ebile re bulehile.Re lebelletse ho emisa le ho theha kamano ea lerato e tšepahalang le ea nako e telele.
MOQ e tlase bakeng saChina Pharmaceutical Intermediate le 330942-05-7, "Boleng bo botle le theko e utloahalang" ke melao-motheo ea rona ea khoebo.Haeba u thahasella litharollo tsa rona kapa u na le lipotso, hopola ho ikutloa u lokolohile ho ikopanya le rona.Re tšepa ho theha likamano tsa tšebelisano le uena nakong e tlang e haufi.

E fetileng: PriceList for High Quality Antiviral Entecavir Powder CAS 142217-69-4 ka Theko e Molemohali

E 'ngoe: MOQ e tlase bakeng sa Thekiso e Chesang!Phepelo ea Feme ea Boleng bo Phahameng Betrixaban Raw Materials CAS 330942-05-7

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