Hydroxypyrazolodpyrimidine pyrazolo(3,4-d)pyrimidin-1-ol
Hydroxypyrazolodpyrimidine pyrazolo(3,4-d)pyrimidin-1-ol
E sebelisoa ka kliniki ho hyperuricemia ea mantlha le ea bobeli, haholo-holo ho bakuli ba nang le hyperuricemia, hammoho le ho bakuli ba nang le ho se sebetse hantle ha renal, le ho bakuli ba nang le gout e iphetang kapa e sa foleng, hammoho le ho bakuli ba nang le Hyperuricemia.E sebelisoa ho bakuli ba nang le Gouty nephropathy ho imolla matšoao le ho fokotsa sebopeho sa majoe a renal uric acid;majoe a gout;e sebelisoang ho uric acid ea liphio le lefu la liphio la uric acid.
Sehlahisoa sena le metabolites ea sona li ka thibela xanthine oxidase, e le hore hypoxanthine le xanthine li se ke tsa fetoloa hore e be uric acid, ke hore, motsoako oa uric acid oa fokotseha, kahoo o fokotsa khatello ea uric acid maling le ho fokotsa bongata ba uric acid. masapo, manonyeletso le liphio, lithethefatsi tse ka thibelang ho qaptjoa ha uric acid.Sehlahisoa sena se ka thibela tšebetso ea li-enzyme tsa lithethefatsi tsa sebete.
(1) .Hyperuricemia ea mathomo le ea bobeli, haholo-holo ba nang le tlhahiso e feteletseng ea uric acid, e boetse e sebelisoa bakeng sa hyperuricemia e nang le ho se sebetse ha renal;
(2) .Bakeng sa phekolo ea gout, e loketseng bakeng sa gout e tloaelehileng kapa e sa foleng.Bakeng sa bakuli ba nang le gouty nephropathy, e ka imolla matšoao le ho fokotsa sebopeho sa majoe a uric acid liphio;
(3) .Tophi;
(4) .E sebelisoa bakeng sa majoe a liphio a uric acid le (kapa) uric acid nephropathy.
Maemo:usp42
Tlhahlobo:98-102%
Kantle:Phofo e tšoeu kapa e batlang e le tšoeu
Sephutheloana :25kg / mokotla
Ho na le khatello ea masapo, e ka bakang pancytopenia, 'me moriana o lokela ho khaotsa ha ho hlokahala.Noa metsi a mangata nakong ea meriana, 'me u etse hore moroto o se nke lehlakore kapa alkaline ho ntša diuretic acid.Sehlahisoa sena se tlameha ho sebelisoa ka mor'a hore ho ruruha ho matla ha ramatiki ea gouty ho nyamele (hangata hoo e ka bang libeke tse peli ka mor'a ho qala).Nakong ea meriana, setšoantšo sa mali le sebete le liphio li lokela ho hlahlojoa khafetsa.
JIN DUN Medical o na leHo tšoaneleha ha ISO mme e kopana le litekanyetso tsa tlhahiso ea GMP, e hirileng litsebi tsa ka hare ho naha le tsa kantle ho naha tse nang le boiphihlelo bo bongata ho tataisa R&D ea k'hamphani.
THEKNOL OGY MELEMO
● High Pressure Catalytic Hydrogenation .Khatello e Phahameng ea Hydrogenolysis Reaction .Mehato ea Cryogenic (<-78%C)
● Monko o monate oa Heterocyclic Synthesis
● Karabelo ea ho Rulahanya bocha
●Chiral Resolution
●Heck, Suzuki,Negishi,Sonogashira .Giignard Reaction
Thepa
Lab ea rona e na le lisebelisoa tse fapaneng tsa liteko le liteko, joalo ka: NMR (Bruker 400M), HPLC, chiral-HPLC, LC-MS, LC-MS/MS (API 4000), IR, UV, GC, GC-MS, Chromatography, Microwave Synthesizer, Parallel Synthesizer, Differential Scanning Calorimeter (DSC), Electron microscope...
Sehlopha sa R&D
Jindun Medical e na le sehlopha sa basebetsi ba profeshenale ba R&D, 'me e sebelisa litsebi tse ngata tsa lapeng le kantle ho naha ho tataisa R&D, ho etsa hore pokello ea rona e nepahale le ho sebetsa hantle.
Re thusitse lik'hamphani tse ngata tse phahameng tsa malapeng tsa meriana, tse kangHansoh, Hengrui le HEC Pharm.Mona re tla bontša karolo ea bona.
Customization Case One:
Cas No.: 110351-94-5
Taba ea Bobeli ea Tloaelo:
Cas No.: 144848-24-8
Taba ea Boraro ea Tloaelo:
Cas No.: 200636-54-0
1.Iketsetse Li-Intermediate tse Ncha kapa li-API.Joalo ka ho arolelana linyeoe tse kaholimo, bareki ba na le litlhoko tsa li-Intermediates kapa li-API, 'me ha ba khone ho fumana lihlahisoa tse hlokahalang' marakeng, joale re ka thusa ho Customize.
2.Ntlafatso ea Ts'ebetso ea Lihlahisoa tsa Khale.Sehlopha sa rona se tla thusa ho ntlafatsa le ho ntlafatsa tlhahiso e joalo eo tsela ea eona ea ho arabela e leng ea khale, litšenyehelo tsa tlhahiso li phahame, 'me katleho e tlaase.Re ka fana ka litokomane tse felletseng bakeng sa phetisetso ea theknoloji le ntlafatso ea ts'ebetso, re thusa moreki bakeng sa tlhahiso e sebetsang hantle.
Ho tloha ho sepheo sa lithethefatsi ho isa ho INDs, JIN DUN Medical e u falitharollo tsa motho ka mong tsa R&D.
JIN DUN Medical e tsitlallela ho theha sehlopha se nang le litoro, ho etsa lihlahisoa tse nang le seriti, tse hlokolosi, tse thata, le ho tsoa bohle ho ba molekane ea tšepahalang le motsoalle oa bareki!
![1,4′-Bipiperidine]-1′-carbonyl chloride HCl](http://cdn.globalso.com/jindunchem-med/image211-300x300.png)
