Tlhaloso e phahameng Phepelo 99% Imidazole/1h-Imidazole/Imz CAS 288-32-4

E inehetse ho taolo e tiileng e matla le k'hamphani e nahanelang ea bareki, basebetsi ba rona ba nang le boiphihlelo hangata ba fumaneha ho buisana ka litlhoko tsa hau le ho fana ka thabo e itseng ea moreki bakeng sa Tlhaloso e Phahameng ea Phano 99% Imidazole/1h-Imidazole/Imz CAS 288-32-4, We' itokiselitse ho sebelisana le metsoalle e metle ea khoebo e tsoang ntlong ea hau le mose ho maoatle le ho etsa nako e telele e ntle ka kopanelo.
E inehetse ho taolo e ntle ka ho fetesisa le k'hamphani e nahanelang ea bareki, basebetsi ba rona ba nang le boiphihlelo hangata ba fumaneha ho buisana ka litlhoko tsa hau le ho etsa hore ho be le thabo e felletseng ea bareki bakeng saChina Imidazole le Imz, Selemo se seng le se seng, bareki ba rona ba bangata ba ne ba etela k'hamphani ea rona mme ba fihlele tsoelo-pele e kholo ea khoebo ba sebetsang le rona.Re u amohela ka tieo hore u re etele ka nako leha e le efe 'me hammoho re tla atleha ho ba le katleho e kholo indastering ea moriri.

E bohareng bakeng sa motsoako oa allopurinol.

Ke e 'ngoe ea lihlopha tsa 3-amino-4-substituted pyrazole.E ka sebelisoa e le setsi sa ho kopanya metsoako e mengata e sebetsang ea pharmacologically, e kang allopurinol, e 'ngoe ea li-derivatives tsa pyrazolopyrimidine, ea morao-rao ho tloha ka 1963 Ho tloha ka tšebeliso ea eona ea bongaka, e bile moriana o ka sehloohong oa phekolo ea gout.Hona joale, ho na le mekhoa e fokolang e tsejoang ea ho kopanya

3-aminopyrazole-4-carboxamide hemisulfate Chaena, haholo-holo ka ho itšoara ka malononitrile le triethyl orthoformate ho lokisetsa ethoxymethylene malononitrile, 'me joale ka Karabelo ea hydrazine hydrate e hlahisa 3-amino-4-cyanopyrazole, e qetellang e arabela ka acid e concentrated ho hlahisa sulfuric acid.

3-aminopyrazole-4-carboxamide hemisulfate (Chen Huiru, Xiao Guomin et al. 3-aminopyrazole- Synthesis of 4-formamide hemisulfate [J]. Chemical Industry Times, 2008, 6 (22): 39 40), kakaretso ea lihlahisoa tsa synthesis ka mokhoa ona ke hoo e ka bang 60% (e baloang e le malononitrile), mokhoa ona E kenyelletsa ho itšoara ka mehato e meraro, mehato e telele, 'me li-reagents tse sebelisoang, tse kang malononitrile le ethoxymethylene malononitrile, li na le chefo e ngata ebile li theko e boima.Ho phaella moo, 3-aminopyrazole-4 e lokiselitsoeng ke mokhoa ona - Formamide hemisulfate e na le 'mala o thata ho o tlosa' me o hloka ts'ebetso e eketsehileng, e leng e rarahaneng haholoanyane.

Ho na le litlaleho libukeng tse tsoang linaheng tse ling tse sebelisang pyridylamide hydrazone le ethoxymethylene malononitrile e le lisebelisoa tse tala ho fumana 3-amino-4-cyanopyrazole ka ho phaella le cyclization, ebe o itšoara ka concentrated sulfuric acid ho fumana motsoako o lebisitsoeng (Reuken G Jones. activemethylene metsoako [J] J Am Chem Soc. 1952,74 (5) :4889 4891).Lisebelisoa tse ka sehloohong tse sebelisoang ka mokhoa ona li theko e boima, lihlahisoa tsa karabelo ha li phahame, 'me phaello ea tlhahiso ea indasteri e tlaase.E tlameha ebe ho thata.

Tekanyetso ea tsamaiso:Maemo a Khoebo
Kantle:Phofo e tšoeu kapa e mosehla

Sephutheloana:25kg / moropa
assay (HPLC) litaba tse kholo ho feta kapa li lekana le 98.0%
bohloeki (HPLC) litaba tse kholo ho feta kapa li lekana le 99.5%

E inehetse ho taolo e tiileng e matla le k'hamphani e nahanelang ea bareki, basebetsi ba rona ba nang le boiphihlelo hangata ba fumaneha ho buisana ka litlhoko tsa hau le ho fana ka thabo e itseng ea moreki bakeng sa Tlhaloso e Phahameng ea Phano 99% Imidazole/1h-Imidazole/Imz CAS 288-32-4, We' itokiselitse ho sebelisana le metsoalle e metle ea khoebo e tsoang ntlong ea hau le mose ho maoatle le ho etsa nako e telele e ntle ka kopanelo.
Tlhaloso e phahamengChina Imidazole le Imz, Selemo se seng le se seng, bareki ba rona ba bangata ba ne ba etela k'hamphani ea rona mme ba fihlele tsoelo-pele e kholo ea khoebo ba sebetsang le rona.Re u amohela ka tieo hore u re etele ka nako leha e le efe 'me hammoho re tla atleha ho ba le katleho e kholo indastering ea moriri.