Boleng bo botle 99% 2-Cyanobenzyl Bromide;Alpha-Bromo-O-Toluonitrile CAS: 22115-41-9

Re ke ke ra leka ka matla ho fana ka lik'hamphani tse ntlehali ho moreki e mong le e mong, empa hape re ikemiselitse ho amohela tlhahiso efe kapa efe e fanoang ke bareki ba rona bakeng sa boleng bo botle ba 99% 2-Cyanobenzyl Bromide;Alpha-Bromo-O-Toluonitrile CAS: 22115-41-9, Sehlopha sa feme ea rona hammoho le ts'ebeliso ea mahlale a morao-rao se fana ka thepa ea boleng bo holimo e ratoang le ho ananeloa ke litebello tsa rona lefatšeng ka bophara.
Re ke ke ra leka ka matla ho fana ka lik'hamphani tse ntlehali ho moreki e mong le e mong, empa hape re ikemiselitse ho amohela tlhahiso efe kapa efe e fanoang ke bareki ba rona bakeng saChina 2-Cyanobenzyl Bromide Powder le Alpha-Bromo-O-Toluonitrile, Re lumela ka tieo hore theknoloji le tšebeletso ke motheo oa rona kajeno le boleng bo tla theha marako a rona a ka tšeptjoang a bokamoso.Ke rona feela ba nang le boleng bo betere le bo betere, re ka fihlelang bareki ba rona le rona ka borona.Amohela bareki hohle ka lentsoe ho ikopanya le rona bakeng sa ho fumana khoebo e eketsehileng le likamano tse tšepahalang.Haesale re le mona re sebeletsa litlhoko tsa hau neng kapa neng ha u hloka.

Sebelisa:E bohareng bakeng sa Linagliptin.

Sebelisa:E bohareng bakeng sa Linagliptin
Boemo ba tsamaiso:maemo a khoebo
Tlhahlobo:98-102%

Kantle:Phofo e tšoeu ho isa ho e mosehla
Sephutheloana:25kg / moropa

Ho sekaseka linagliptin e teng le senotlolo sa eona sa mahareng 8-bromo-7-(2-butynyl)-3,7-dihydro-3-methyl-1--[(4-methyl -2-quinazolinyl)methyl)-1H-purine- 2,6-dione (11) mokhoa oa ho kopanya, fumana tsela ea maiketsetso e loketseng tlhahiso ea indasteri.Mokhoa: akaretsa litsela tse fapaneng tsa maiketsetso.Liphetho le liqeto: Route 2.2 e na le ts'ebetso e batlang e le bonolo le litšenyehelo tse tlase, tse loketseng tlhahiso ea indasteri.

8-bromo-3,7-dihydro-3-methyl-1H-purine-2,6-dione ke karolo e ka sehloohong ea motsoako oa motsoako oa lithethefatsi tsa hypoglycemic linagliptin.The synthesis ea 1 e sebelisa methyl urea le cyanoacetic acid e le lisebelisoa tsa ho qala, 'me e kena mehatong e tšeletseng ea condensation, cyclization, nitrosation, fokotsa, cyclization, le bromine ka lihlahisoa tse feletseng tsa 46.3%.Mehaho ea li-intermediate tsohle e tiisitsoe ke 1HNMR.

Moqapi oa hona joale o amana le mokhoa o bonolo oa ho itokisa oa linagliptin.Quinazoline, senotlolo sa bohareng bakeng sa ho lokisa pitsa e le 'ngoe ea linagliptin 8 bromo 7 (2 butyne 1 base) 3,7 dihydro 3 methyl 1 [(4 methyl 2 quinazolinyl) methyl] 1H Purine 2,6 dione, e bohareng e arotsoe ke filtration, 'me ka mor'a moo a itšoara ka (R)3 aminopiperidine dihydrochloride ho fumana tharollo e nang le linagliptin.Kamora hore tharollo e nang le linagliptin e sebetsoe hape, sehlahisoa se hloekileng sa Deliraliptin.Ho lokisoa ha senotlolo sa bohareng ba boqapi ba hona joale ho nka mokhoa oa pitsa e le 'ngoe, e loketseng ho sebetsa le ho ntlafatsa chai.Ka mor'a hore senotlolo sa bohareng se arohane, se sebetsanoa le (R) 3 aminopiperidine dihydrochloride, ka tsela eo Ho fumana linagliptin e phahameng ka ho fetisisa e kopana le litlhoko tsa tlhahiso le phatlalatso ea lik'hamphani tsa meriana ka tekanyo e kholo ka ho fetisisa.

Re ke ke ra leka ka matla ho fana ka lik'hamphani tse ntlehali ho moreki e mong le e mong, empa hape re ikemiselitse ho amohela tlhahiso efe kapa efe e fanoang ke bareki ba rona bakeng sa boleng bo botle ba 99% 2-Cyanobenzyl Bromide;Alpha-Bromo-O-Toluonitrile CAS: 22115-41-9, Sehlopha sa feme ea rona hammoho le ts'ebeliso ea mahlale a morao-rao se fana ka thepa ea boleng bo holimo e ratoang le ho ananeloa ke litebello tsa rona lefatšeng ka bophara.
Boleng bo botleChina 2-Cyanobenzyl Bromide Powder le Alpha-Bromo-O-Toluonitrile, Re lumela ka tieo hore theknoloji le tšebeletso ke motheo oa rona kajeno le boleng bo tla theha marako a rona a ka tšeptjoang a bokamoso.Ke rona feela ba nang le boleng bo betere le bo betere, re ka fihlelang bareki ba rona le rona ka borona.Amohela bareki hohle ka lentsoe ho ikopanya le rona bakeng sa ho fumana khoebo e eketsehileng le likamano tse tšepahalang.Haesale re le mona re sebeletsa litlhoko tsa hau neng kapa neng ha u hloka.